Parker A., Maclaren O.J., Fletcher A.G., Muraro D., Kreuzaler P.A., Byrne H.M., Maini P.K., Watson A.J.M., and Pin C. (2017) Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi. FASEB Journal. 31: 636-649 http://www.fasebj.org/content/early/2016/10/19/fj.201601002.abstract In this paper, we have demonstrated that cell proliferation within crypts is a principal […]
Publication
Maclaren, A. Parker, C. Pin, S.R. Carding, A.J.M. Watson, A.G. Fletcher, H.M. Byrne and P.K. Maini. (2017). A hierarchical Bayesian framework for understanding the spatiotemporal dynamics of the intestinal epithelium. PLoS Computational Biology, 28;13(7):e1005688 We have addressed two key challenges, one biological and one methodological. First, we have developed new understanding on how proliferation rates, […]
Project meeting on October 8th, 2015
We met in London
Project meeting on April 27th 2015
All partners met in London
Project meeting Sept 16th, 2014
Partners met in Norwich to discuss results
EMBO|EMBL Symposium on Epithelia: the building Blocks of Multicellularity
We attended the Symposium in Heidelberg (27-30 Aug 2014) and presented a Poster: Understanding crypt-villus homeostasis and recovery in the intestinal epithelium: experiments and mathematical models.
Project meeting May 28th, 2014
All partners met in London to discuss modelling and experimental approaches for cell proliferation and migration in the intestinal epithelium
Project website launched
This new website for the ‘Decrypting the Villus’ project, coordinated by the Institute of Food Research, highlights the main aims of the project and will be used to communicate major outputs during the lifetime of the project. The website includes a blog which will be regularly updated by the participants and we welcome feedback via […]
New funding award from BBSRC
IFR scientist Dr Carmen Pin has been awarded funding of just over £467,000 from the Biotechnology and Biological Sciences Research Council (BBSRC) to answer fundamental questions on the regulation of the intestinal epithelium, and to contribute to the identification of strategies for maintaining the health and preventing diseases of the gastrointestinal tract. The award is based […]
